CVS 

CVS (chorionic villus sampling)

Chorionic villus sampling (CVS) means sampling of chorionic villi (placental tissue), which is recommended in pregnancies at high risk of fetal chromosomal defects. Its aim is to exclude or confirm any fetal genetic anomaly. CVS can be performed from 11-14 weeks, thus earlier than amniocentesis with the advantage of an early exclusion or confirmation of any fetal genetic anomaly.

Before the procedure itself we first evaluate by scan the placental position and find the best place for a needle insertion. After applying a local anaesthetic,, a fine needle is passed through the mother’s abdomen and a sample of villi is taken. The movement of the needle is carefully controlled using an ultrasound scan. The sample of villi is then sent for genetic analysis to a cytogenetic laboratory. Both the baby and placenta originate from the same cell so the chromosomes present in the cells of the placenta will be the same as those of the baby. Because a needle needs to be inserted into the uterine cavity, CVS is an invasive test and slightly increases the risk of miscarriage (by about 0.5%, about the same as at amniocentesis). The procedure itself is not very painful. After the procedure you may experience some abdominal discomfort or period-like pain, but this should resolve within 1 – 2 days. You may find it helpful to take a basic painkiller such as paracetamol.

First results regarding the presence of the most frequent chromosomal defects are available within 2 working days after procedure with the complete results available usually within 2 weeks. You will be informed of the initial results by a phone call from us or the clinical geneticist. Complete results should be passed to you at counselling so are sent to a clinical geneticist, who will also be able explain them fully to you.

Further recommended scans in case of normal result:

Call: +420 737 220 878

Pregnancy care Invasive tests CVS